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SEP
1
Electrophysiology & Imaging Techniques for Cell Physiology
Virtual Workshop
SEP
2
New Roles for Ion Channels and Transporters in Health and Disease
Online Symposium
SEP
7
SEP
16
SEP
22
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Fundamentals
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What are ion channels?
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Nobel Prizes
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History of ion channels
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Why we should care about ion channels
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Extraordinary ordinary patch-clamp
The paper on patch-clamping by Erwin Neher and Bert Sakmann (1976) has been selected as 1 out of 10 extraordinary Nature papers.
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Membrane transport
Every cell possesses a variety of sophisticated membrane transport systems allowing for control of the intracellular environment.
Interviews
Articles Pubmed
- Electrophysiological modeling of the effect of potassium channel blockers on the distribution of stimulation wave in the human gastric wall cells. J Biomech. 2021 Aug 4.
- The role of voltage-gated chloride channels in the epileptogenesis of temporal lobe epilepsy. EBioMedicine. 2021 Aug 11.
- Physical basis for distinct basal and mechanically gated activity of the human K(+) channel TRAAK. Neuron. 2021 Aug 11
- RyR-mediated Ca2+ release elicited by neuronal activity induces nuclear Ca2+ signals, CREB phosphorylation, and Npas4/RyR2 expression. Proc Natl Acad Sci U S A. 2021 Aug 17.
- Physical basis for distinct basal and mechanically gated activity of the human K(+) channel TRAAK. Neuron. 2021 Aug 11
preprints bioRxiv
- The diazepam binding inhibitor’s modulation of the GABA-A receptor is subunit-dependent
- Sulfonylureas target the neurovascular response to decrease Alzheimer’s pathology
- Structural modeling of the hERG potassium channel and associated drug interactions
- Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension
- Kv4.3 channel downregulation mediates chronic post-lesional pacemaker acceleration in surviving dopamine substantia nigra neurons
- Variant landscape of the RYR1 gene based on whole genome sequencing of the Singaporean population
PATENTS GOOGle patents
- The diazepam binding inhibitor’s modulation of the GABA-A receptor is subunit-dependent
- Sulfonylureas target the neurovascular response to decrease Alzheimer’s pathology
- Structural modeling of the hERG potassium channel and associated drug interactions
- Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension
- Kv4.3 channel downregulation mediates chronic post-lesional pacemaker acceleration in surviving dopamine substantia nigra neurons
- Variant landscape of the RYR1 gene based on whole genome sequencing of the Singaporean population
CLINICAL TRIALS ClinicalTrials
- The diazepam binding inhibitor’s modulation of the GABA-A receptor is subunit-dependent
- Sulfonylureas target the neurovascular response to decrease Alzheimer’s pathology
- Structural modeling of the hERG potassium channel and associated drug interactions
- Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension
- Kv4.3 channel downregulation mediates chronic post-lesional pacemaker acceleration in surviving dopamine substantia nigra neurons
- Variant landscape of the RYR1 gene based on whole genome sequencing of the Singaporean population
Ion Channels on Social media
- Electrophysiological modeling of the effect of potassium channel blockers on the distribution of stimulation wave in the human gastric wall cells. J Biomech. 2021 Aug 4.
- The role of voltage-gated chloride channels in the epileptogenesis of temporal lobe epilepsy. EBioMedicine. 2021 Aug 11.
- Physical basis for distinct basal and mechanically gated activity of the human K(+) channel TRAAK. Neuron. 2021 Aug 11
- RyR-mediated Ca2+ release elicited by neuronal activity induces nuclear Ca2+ signals, CREB phosphorylation, and Npas4/RyR2 expression. Proc Natl Acad Sci U S A. 2021 Aug 17.
- Physical basis for distinct basal and mechanically gated activity of the human K(+) channel TRAAK. Neuron. 2021 Aug 11
- The diazepam binding inhibitor’s modulation of the GABA-A receptor is subunit-dependent
- Sulfonylureas target the neurovascular response to decrease Alzheimer’s pathology
- Structural modeling of the hERG potassium channel and associated drug interactions
- Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension
- Kv4.3 channel downregulation mediates chronic post-lesional pacemaker acceleration in surviving dopamine substantia nigra neurons
- Variant landscape of the RYR1 gene based on whole genome sequencing of the Singaporean population
- The diazepam binding inhibitor’s modulation of the GABA-A receptor is subunit-dependent
- Sulfonylureas target the neurovascular response to decrease Alzheimer’s pathology
- Structural modeling of the hERG potassium channel and associated drug interactions
- Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension
- Kv4.3 channel downregulation mediates chronic post-lesional pacemaker acceleration in surviving dopamine substantia nigra neurons
- Variant landscape of the RYR1 gene based on whole genome sequencing of the Singaporean population
CLINICAL TRIALS ClinicalTrials
- The diazepam binding inhibitor’s modulation of the GABA-A receptor is subunit-dependent
- Sulfonylureas target the neurovascular response to decrease Alzheimer’s pathology
- Structural modeling of the hERG potassium channel and associated drug interactions
- Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension
- Kv4.3 channel downregulation mediates chronic post-lesional pacemaker acceleration in surviving dopamine substantia nigra neurons
- Variant landscape of the RYR1 gene based on whole genome sequencing of the Singaporean population
Ion Channels on Twitter
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