Alfred Nobel

Fundamentals

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Nobel Prizes

The scientific community has recognized the crucial importance of ion channel research by four Nobel Prizes for the discoveries concerning the structure and function of ion channels.

1963

The Nobel Prize in Physiology or Medicine

Sir John Eccles, Alan L. Hodgkin, Andrew F. Huxley

For their discoveries concerning the ionic mechanisms involved in excitation and inhibition in the peripheral and central portions of the nerve cell membrane.

1991

The Nobel Prize in Physiology or Medicine

Erwin Neher, Bert Sakmann

For their discoveries concerning the function of single ion channels in cells.

2003

The Nobel Prize in Chemistry

Peter Agre, Roderick MacKinnon

For the discovery of water channels (P. Agre) and for structural and mechanistic studies of ion channels (R. MacKinnon).

2021

The Nobel Prize in Physiology or Medicine

David Julius, Ardem Patapoutian

For their discoveries of receptors for temperature and touch.

Other Nobel Prizes related to the ion channel field

1932

The Nobel Prize in Physiology or Medicine

Sir Charles Sherrington, Edgar Adrian

For their discoveries regarding the functions of neurons.

1936

The Nobel Prize in Physiology or Medicine

Sir Henry Dale, Otto Loewi

For their discoveries relating to chemical transmission of nerve impulses.

1944

The Nobel Prize in Physiology or Medicine

Joseph Erlanger, Herbert S. Gasser

For their discoveries relating to the highly differentiated functions of single nerve fibres.

1970

The Nobel Prize in Physiology or Medicine

Sir Bernard Katz, Ulf von Euler, Julius Axelrod

For their discoveries concerning the humoral transmittors in the nerve terminals and the mechanism for their storage, release and inactivation.

2000

The Nobel Prize in Physiology or Medicine

Arvid Carlsson, Paul Greengard, Eric R. Kandel

For their discoveries concerning signal transduction in the nervous system.

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History of ion channels