Ion Channel Drugs

Ion channels are now considered to be important drug targets for the treatment of such diseases as cardiac arrhythmia, hypertension, anxiety, epilepsy, and diabetes. In fact, ion channels currently represent the second largest drug target class after G-protein coupled receptors (GPCRs). Nearly 18% of all existing drugs exert their therapeutic activity through ion channels. And here they are.

Ion Channel Drugs on the Market

Drugs

Ion Channel Drugs in Preclinical Development and Clinical Trials

Drugs

Ion channel drugs on the WHO’s List of Essential Medicines

Drugs

Withdrawn / Discontinued Ion Channel Drugs

Drugs


Sources

Want to know more about a particular drug? Here are the principle sources.

DRUGBANK

The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.

DrugCentral

DrugCentral provides information on active ingredients chemical entities, pharmaceutical products, drug mode of action, indications, pharmacologic action.

Drugs

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.

WHO Essential Medecines

Essential medicines are those that satisfy the priority health care needs of the population. They are selected with due regard to public health relevance, evidence on efficacy and safety, and comparative cost-effectiveness.