metallic keys

Image by Uwe Baumann from Pixabay



The classic paper by Neher and Sakmann is 1 out of 10 key Nature papers

The title of this news is self-explanatory. The paper on patch-clamping by Erwin Neher and Bert Sakmann (1976) has indeed been selected as 1 out of 10 extraordinary Nature papers.

Each of these 10 papers revolutionized science and our life. All these are greatest discoveries and it’s a pleasure to see patch-clamp among them.

Nature described our dear patch-clamp as “a breakthrough method that became vital to neuroscience” and listed it side by side with such revolutionary discoveries as the discovery of a composite particle kaon, the first-ever production of monoclonal antibodies, the finding of Australopithecus, the discovery of cage-like carbon molecule, the discovery of the Antarctic ozone hole, the synthesis of ordered mesoporous molecular sieves, the discovery that cell differentiation can be reversed, the discovery of the helical structure of double-stranded DNA and the detection of the first exoplanet around a Sun-like star.

What a collection! Amazing discoveries!

It is somewhat unexpected and unusual to see patch-clamp alongside ozone holes and exoplanets, but this selection of key papers makes us think about the real longlasting impact and extraordinary value of patch-clamp.

I highly recommend you read the full text on

Have an extraordinary patching experience!