Latest

Research highlights

Research

Source: Children’s Hospital of Philadelphia

The recurrent SCN1A p.R1636Q variant causes a clinical entity with a wider clinical spectrum than previously reported, characterized by neonatal onset epilepsy and absence of prominent movement disorder.
Research

Source: Aarhus University

Challenged urine bicarbonate excretion may be an in vivo biomarker of cystic fibrosis transmembrane conductance regulator (CFTR) function.
Research

Source: Imperial College London

The high-throughout, cellular-resolution imaging data indicate that Vm fluctuates dynamically in subpopulations of highly aggressive breast cancer cell lines.
Research

Source: Weill Cornell Medicine

Anionic lipids unlock the gates of select ion channels in the pacemaker family

Upcoming Events

Meeting

December 6-8, 2022

Abstract submission deadline: November 15, 2023

Lille, France

Webinar

December 13, 2022

Organized by: Angelika Lampert and Hugues Abriel

Annual Meeting

February 18-22, 2023

Abstract submission deadline: January 5, 2023

San Diego, CA, USA

Featured Recurring Events

Webinar series

Next webinar: 13/12/2022

Featured

Lecture series bringing together sodium channel researchers worldwide.

WEBINAR SERIES

Next webinar: 14/12/2022

Featured

A virtual platform for the exchange of ideas and discussion on topics related to ion channels and transporters in immunity.

Webinar series

Next webinar: 2023

Featured

Webinar series on all things ion channels.

Symposium

Next symposium: 2023

Featured

A high-level ion channel drug discovery symposium bringing together researchers from academia and industry.

Careers

Careers

Industry

Featured

Metrion Biosciences, Cambridge, UK

Source: Metrion

Careers

Industry

Featured

Metrion Biosciences, Cambridge, UK

Source: Metrion Biosciences

Careers

Academia

UCSF Cardiovascular Research Institute, San Francisco, USA

Source: jobRxiv

Careers

Academia

Weill Cornell Medicine, New York, NY, USA

Source: Nature careers

Careers

Industry

Featured

Nanion Technologies, Livingston, New Jersey, USA

Source: Nanion

Careers

Industry

Nanion Technologies, Munich, Germany

Source: Nanion

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In the Spotlight

Metrion Biosciences is a UK-based pre-clinical CRO providing highly skilled electrophysiology screening services to support client medicinal chemistry optimisation programmes, CiPA-compliant cardiac safety profiling assays, neuroscience assays and translational assays.

Research highlights

Research

Source: University College London

UCL researchers developed a gene therapy strategy that self-selects pathologically overactive neurons and down-regulates their excitability via controlled expression of Kv1.1.
cancer-cells

Research

Source: Johns Hopkins Medicine

Elevated viscosity counterintuitively increases the motility of various cell types in a TRPV4-dependent manner.

Ion channel research in numbers

Fundamentals

ion channel surface

Fundamentals

What are ion channels?

Alfred Nobel

Fundamentals

Nobel Prizes

a hand with lightnings inside

Fundamentals

Why we should care about ion channels

“… ion channels are the most important single class of proteins that exist in the human body or any body…” – Clay Armstrong
Galvani experiment

Fundamentals

History of ion channels

Before the 1660s the Theory of Animal Spirits dominated thinking regarding the function of the nervous system. “Animal spirits” (originating in the brain) were believed to control movements of the body by flowing through the nerves into the muscles.