Research highlights


Source: University College Dublin

New study identifies the TRPV4 channel as playing a key role in translating mechanical signals from a baby’s movement in the womb to healthy development of the skeleton.

Source: Flinders University

Targeting Piezo2 could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome.

Source: Harvard John A. Paulson School of Engineering and Applied Sciences

A new method for modulating neural activity using optogenetic polymerization and assembly of electroactive polymers on specified cellular membranes.

Source: Children’s Hospital of Philadelphia

The recurrent SCN1A p.R1636Q variant causes a clinical entity with a wider clinical spectrum than previously reported, characterized by neonatal onset epilepsy and absence of prominent movement disorder.

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Research highlights

urine test


Source: Aarhus University

Challenged urine bicarbonate excretion may be an in vivo biomarker of cystic fibrosis transmembrane conductance regulator (CFTR) function.
cancer cells


Source: Imperial College London

The high-throughout, cellular-resolution imaging data indicate that Vm fluctuates dynamically in subpopulations of highly aggressive breast cancer cell lines.

Ion channel research in numbers


ion channel surface


What are ion channels?

Alfred Nobel


Nobel Prizes

a hand with lightnings inside


Why we should care about ion channels

“… ion channels are the most important single class of proteins that exist in the human body or any body…” – Clay Armstrong
Galvani experiment


History of ion channels

Before the 1660s the Theory of Animal Spirits dominated thinking regarding the function of the nervous system. “Animal spirits” (originating in the brain) were believed to control movements of the body by flowing through the nerves into the muscles.